Department of Preventive Medicine WHI - Fat Reduction, HRT use and Benign Breast Disease
Principal Investigator
Dorothy Lane, MD, MPH
Co-Principal
Investigator
Iris Granek, MD, MS
“Fat reduction, HRT Use and Benign Breast
Disease Risk” is another ancillary study of the Women’s Health Initiative (WHI)
clinical trials that is studying the effect of the interventions of low-fat diet, HRT use
and calcium/vitamin D use on the risk of benign breast disease (BBD).One model of the natural history of breast cancer
is that it arises as a result of the progression of breast tissue through specific
histological forms of BBD.
